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Malaria is a potentially deadly infectious disease that is spread by mosquitoes. The disease, which typically appears about 10 to 15 days after an infected mosquito bites a human or other animal, generally results in symptoms such as fever, fatigue, vomiting, and headaches. In more serious cases, however, malaria can result in death. No vaccine exists for malaria, but the disease can be treated with a variety of drugs. Malaria is generally found in tropical regions of Asia, Latin America, and sub-Saharan Africa. Some 228 million cases of malaria were recorded in 2018, resulting in just over 400,000 deaths.